03

Unravel the neuropathology of Alzheimer’s disease

Our knowledge of Alzheimer’s disease pathology has advanced significantly since Dr Alois Alzheimer first described it. What is the current understanding of Alzheimer’s disease neuropathology and how does it impact development of symptoms?

15 to 20 years
before symptoms appear, Alzheimer’s disease pathology may be present1

Up to 2 out of 3 patients
with amnestic MCI have underlying Alzheimer’s disease pathology2

‘There's been a revolution in the field...for the first time we can actually watch the build-up of amyloid in the brain.’

Prof Colin Masters

Discover more

THE AMYLOID PUZZLE

Prof Colin Masters and A/Prof David Darby share their insights into the current concepts and controversies in the neurobiology of Alzheimer’s disease on the MindChangers podcast.

Login Required

EXPLORING PATHOLOGICAL OBSTACLES

An expert panel discusses the diagnostic challenges of mixed pathology in patients with Alzheimer’s disease through a patient case study at the International Conference on Alzheimer’s and Parkinson’s Disease (AD/PD) 2019.

Login Required

BRAIN BANKS AND ALZHEIMER'S DISEASE

A/Prof Greg Sutherland, Deputy Director of the NSW Tissue Resource Centre, explains how brain banks can further our understanding of the early changes associated with Alzheimer’s disease and why brain banks will be important to future research.

Login Required

'I think amyloid is critical, [although] it may not be the only thing that’s necessary for Alzheimer’s disease.'

A/Prof David Darby

References: 1. Counts SE et al. Neurotherapeutics. 2017;14(1):35–53. 2. Frisoni GB et al. Lancet Neurol. 2017;16:661–76.